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KMID : 0359320000400010138
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Korean Journal of Veterinary Research
2000 Volume.40 No. 1 p.138 ~ p.144
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Experimental infection of Korean Neospora caninum isolates in mice
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김재훈/Kim, Jae Hoon
김대용/현병화/황우석/최양규/허권/김기석/Kim, Dae Yong/Hyun, Byung Hwa/Hwang, Woo Suk/Choi, Yang Kyu/Hur, Kwon/Kim, Ki Seuk
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Abstract
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This study was carried out to investigate the pathogenicity of Korea N caninum isolates, KBA-1 and KBA-2 on SCID mouse following 3 different routes of infection. NC-1 was served as reference isolate. The pathogenecity was evaluated by progression of clinical signs, histopathology and immunohistochemistry. Pathogenicity of KBA-2 appears to be stronger than that of KBA-1 but weaker than that of NC-1. Progress of clinical signs and lesion distribution and pattern of each isolates were similar when the isolates were infected either subcatareously or intraperitoneally. However, oral inoculation of tachyzoites failed to induce the infection.
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KEYWORD
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